Comparison of quality-of-life
instruments in adults with strabismus.
(Outils de comparaison de la qualité de vie des adultes strabiques)
Hatt SR, Leske DA, Bradley EA,
Cole SR, Holmes JM.
Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota 55905, USA.
PURPOSE: To compare two
health-related quality-of-life (HRQOL) questionnaires in adults with strabismus:
the new 20-item Adult Strabismus (AS-20) questionnaire (developed specifically
for Adult Strabismus) and the 25-item National Eye Institute Visual Function
Questionnaire (VFQ-25).
DESIGN: Cross-sectional study.
METHODS: Eighty-four adult patients with strabismus (median age, 53 years;
range, 18 to 81 years) completed the AS-20 and VFQ-25 HRQOL questionnaires.
Patients were categorized as diplopic (n = 65) or nondiplopic (n = 19).
Subnormal HRQOL was defined as less than the fifth percentile for adults with no
visual impairment. The proportion of patients below normal was compared overall
and by diplopia status.
RESULTS: Overall, more patients scored below normal with the AS-20 than
with the VFQ-25 (90% vs 29%; P < .0001). Nondiplopic patients more often were
below normal on the AS-20 psychosocial subscale than on the function subscale
(95% vs 42%; P = .002), whereas diplopic patients were more often below normal
on the function subscale (85% vs 68%; P = .01). On the psychosocial subscale,
more nondiplopic than diplopic patients scored below normal (95% vs 68%; P =
.01); on the function subscale, more diplopic than nondiplopic patients scored
below normal (85% vs 42%; P = .0005). The VFQ-25 seemed to be insensitive to
nondiplopic strabismus: no patients scored below normal on composite score and
no more than 11% scored below normal on VFQ-25 subscales. Of diplopic patients,
37% scored below normal on VFQ-25 composite score. No more than 38% scored below
normal on VFQ-25 subscales.
CONCLUSIONS: The new AS-20 seems to be more sensitive than the VFQ-25 for
detecting reduced HRQOL in Adult Strabismus, and therefore may be a more useful
tool for clinical assessment and clinical trials.
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bibliographie de Septembre 2009
(Dernière mise à jour de cette page le 27/08/10)